周选围
职称:教授
研究方向:
(1)食药用真菌生物技术
(2)药用真菌资源的开发与利用
电话:021-34205778 

传真:021-34205778
电子信箱:
xuanweizhou@163.com

                     xuanweizhou@sjtu.edu.cn

     

 

个人简介

      周选围,男,1962年生,博士,陕西咸阳人。manbetx体育3.0下载教授。1984大学本科毕业在陕西理工大学参加工作,至2004年,历任助教、讲师、副教授、教授;其中1990~1991年在华东师范大学学习硕士学位课程; 2011-2014年在上海师范大学学习并获得博士学位,2002~2004年在复旦大学遗传研究所合作研究,2011~2012在美国马里兰大学(University of Maryland College Park, MD)访问学者。2004年11月至今在manbetx体育3.0下载植物科学系、植物生物技术研究中心工作。

 

研究项目

      1.主持:利用生物技术开发青稞功能性活性成分.天津汇禾食品有限公司. 执行年限:2016.09-2019.09. 经费:40万(在研)

     2.主持:“冬虫夏草资源的保护和可持续利用的研究”. 西藏圣龙实业有限公司. 资助经费:100万元,执行年限:2013.01-2017.12。(在研)

     3.主持:“冬虫夏草人工辅助生长技术方案的研究”. 西藏圣牛生物科技有限公司. 资助经费 10 万。执行年限:2012-2014. (已结题)

     4.主持:“利用DNA改组技术优化真菌免疫调节蛋白基因” (项目编号:30771500),国家自然科学基金面上项目,资助经费:29万元;执行年限:2008.1-2010.12.

     5.主持:“产紫杉醇内生真菌基因工程改良的研究”(项目编号:07DZ17924),上海市科委中药现代化专项基金,资助经费:60万元,执行年限:2007.9-2010.9.

     6.主持:“灵芝生药质量分子检测技术的研究” (项目编号:05DZ05007),上海市科委专项基金,项目经费:15/55万,2005.10-2007.09.

     7.主持: “蛹虫草产品开发与利用”. 吴江市太湖蚕业科技开发有限公司. 资助经费:3万元;执行年限:2010.10-12。(已结题)

 

专利与奖励

      获得国家授权的发明专利9项(附后);2000年“灵芝的综合开发和利用”获陕西省教育厅科技进步二等奖 ;1999年《生物教学论》课的教学方法改革—探索发展学生能力的一般途径,获教育部办公厅“世界银行贷款师范教育发展项目改革课题”优秀成果三等奖。“生物技术教育课程建设与应用”获得上海交通大学2015年度教学成果奖、校长教学奖二等奖。

 

主要论著

      [1] 主编:《生物技术概论》(高等教育出版社,2010;国家十二五规划教材)。

     [2] 主编:《天然抗癌植物资源与开发利用》(西北大学出版社,1999)。

     [3] 编著:《学业评价的原理与技术》(陕西师范大学出版社,2002)。

     [4] 参编:《Edible and Medicinal Mushrooms: Technology and Application》(John Wiley & Sons Ltd, 2017)。

     [5] 参编:《中草药生物技术》(复旦大学出版社,2005)。

     [6] 参编:《体外培养的原理和技术》(科学出版社,2001)。

 

代表论文(SCI收录,仅第一和通讯作者*

     [1] Xu H, Guo MY, Gao YH, Bai XH,Zhou XW*. Expression and characteristics of manganese peroxidase from Ganoderma lucidum in Pichia pastoris and its application in the degradation of four dyes and phenol. BMC Biotechnology. 2017, 17:19.

     [2] Guo MY, Liu Y, Gao YH, Jin T, Zhang HB, Zhou XW*.  Identification and Bioactive Potential of Endogenetic Fungi Isolated from Medicinal Caterpillar Fungus Ophiocordyceps sinensis from Tibetan Plateau. International Journal of Agriculture & Biology. 2017, 19(2):307-313.

     [3] Xia F, Chen X, Guo MY, Bai XH, Liu Y, Shen GR, Li YL, Lin J, Zhou XW*. High-throughput sequencing-based analysis of endogenetic fungal communities inhabiting the Chinese Cordyceps reveals unexpectedly high fungal diversity. Scientific Reports. 2016, 6:33437.

     [4] Xu H, Kong YY, Chen X, Guo MY, Bai XH, Lu YJ, Li WZhou XW*. Recombinant FIP-gat, a Fungal Immunomodulatory Protein from Ganoderma atrum, Induces Growth Inhibition and Cell Death in Breast Cancer Cells. Journal of Agricultural and Food Chemistry. 2016, 64(13):2690-2698.

     [5] Xia F, Liu Y, Guo MY, Shen GR, Lin J, Zhou XW*. Pyrosequencing analysis revealed complex endogenetic microorganism community from natural DongChong XiaCao and its microhabitat. BMC Microbiology. 2016, 6(1):196.

     [6] Zhou XW*, Liu Yan, Su KQ, Zhang YM. Species Clarification of the Widely Cultivated Ganoderma in China Based on rDNA and FIP Gene Sequence Analysis. International Journal of Agriculture & Biology. 2016, 18(5):932- 938.

     [7] Xia F, Liu Y, Shen GR, Lin J, Zhou XW*. Investigation and Analysis of Microbiological Communities in Natural Ophiocordyceps sinensis. Canadian Journal of Microbiology. 2015, 61(2): 104-111

     [8] Zhou XW*, Su KQ, Zhang YM. Phylogenetic analysis of widely cultivated Ganoderma in China based on the mitochondrial V4-V6 region of SSU rDNA. Genetics and Molecular Research. 2015,14(1): 886-897.

     [9] Zhou XW*, Li LJ, Tian EW.Advances in research of artificial cultivation of Ophiocordyceps sinensis in China. Critical Review in Biotechnology. 2014, 34(3): 233-43.

     [10] Cong WR, Xu H, Liu Y, Li QZ, Li W, Zhou XW*. Production and functional characterization of a novel fungal immunomodulatory protein FIP-SN shuffled from two genes of Ganoderma species. Applied Microbiology and Biotechnology. 2014, 98(13):5967-75.

     [11] Cong WR, Liu Y, Li QZ, Zhou XW*. Cloning and analysis of a functional promoter of fungal immunomodulatory protein from Flammulina velutipes. Molecular Biology Reports. 2014, 41(7):4381-7.

     [12] Cong WR, Gong ZH, Shi DD, Zhou XW*. Cloning and analysis of mating-type gene MAT1-1-1 from Cordyceps militaris. International Journal of Medicinal Mushrooms. 2014, 16(5) : 449-462.

     [13] Liu Y, Yuan WN, Zhou XW*. Optimization of submerged culture conditions for the mycelial biomass and bioactive metabolites production by Cordyceps militaris. Journal of Pure and Applied Microbiololgy. 2014, 8(6): 4245-4254.

     [14] Wang XF, Li QZ, Bao TW, Cong WR, Zhou XW*.In vitro rapid evolution of fungal immunomodulatory proteins by DNA family shuffling. Applied Microbiology and Biotechnology. 2013, 97(6): 2455-2465.

     [15] Zhou XW*, Cong WR, Su KQ, Zhang YM. Ligninolytic enzymes from Ganoderma spp.-Current status and potential applications. Critical Review in Microbiology. 2013, 39(4):416-26

     [16]  Zhou XW*, Su KQ, Zhang YM. Applied modern biotechnology for cultivation of Ganoderma and development of their products. Applied Microbiology and Biotechnology. 2012, 93(3):941-963.

     [17] Zhou XW*, Wang XF, Li QZ. Expression and characteristic of the Cu/Zn superoxide dismutase gene from the insect parasitizing fungus Cordyceps militaris. Molecular Biology Reports. 2012, 39(12):10303-10311.

     [18] Wang XF, Su KQ, Bao TW, Cong WR, Chen YF, Li QZ, Zhou XW*. Immunomodulatory effects of fungal proteins. Current Topics in Nutraceutical Research. 2012,10 (1): 1-11.

     [19] Li QZ, Huang L, Wang XF, Li XS, Wu SQ, Zhou XW*. Fungal immunomodulatory protein from Flammulina velutipes induces cytokine gene xpression in mouse spleen cells. Current Topics in Nutraceutical Research. 2011, 9(3): 111-118.

     [20] Li QZ, Wang XF, Zhou XW*. Recent status and prospects of the fungal immunomodulatory protein family. Critical Reviews in Biotechnology. 2011, 31(4): 365-375.

     [21] Li QZ, Zheng SB, Wang XF, Bao TW, Zhou XW*. Preparation of rabbit anti-Ganoderma sinensis immunomodulatory protein polyclonal antibody. African Journal of Microbiology Research. 2011, 5(12): 1562-1564.

     [22] Li QZ, Wang XF, Bao TW, Ran L, Lin J, Zhou XW*. In vitro synthesis of a recombinant fungal immunomodulatory protein from Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W.Curt.:Fr.) P.Karst. (Aphyllophoromycetideae) and analysis of its immunomodulatory activity. International Journal of Medicinal Mushrooms, 2010, 12(4):347–358.

     [23] Li QZ, Wang XF, Chen YY, Lin J, Zhou XW*. Cytokines expression induced by Ganoderma sinensis fungal immunomodulatory proteins (FIP-gsi) in mouse spleen cells. Applied Biochemistry and Biotechnology. 2010, 162(5):1403-1413.

     [24] Zhou XW*, Zhu HF, Liu L, Lin J. Recent advances and prospect on taxol-producing endophytic fungi. Applied Microbiology and Biotechnology. 2010, 86(6): 1707-1717.

     [25] Zhou XW*, Xie MQ, Hong F, Li QZ, Lin J. Genomic clones and characterization of a FIP-gsi gene encoding a fungal immunomodulatory protein from Ganoderma sinensis. International Journal of Medicinal Mushrooms. 2009, 11(1):77-86.

     [26] Zhou XW*, Zheng WL, Zhu HF, Tang KX. Identification of a taxol-producing endophytic fungus EFY-36. African Journal of Biotechnology. 2009, 2009, 8(11): 2623-2625.

     [27] Gong ZH, Su Y, Huang L, Lin J, Tang KX, Zhou XW*. Cloning and analysis of glyceraldehyde-3- phosphate dehydrogenase gene from Cordyceps militaris. African Journal of Agricultural Research. 2009, 4(4): 402-408.

     [28] Huang L, Li QZ, Chen YY, Wang XF, Zhou XW*. Determination and analysis of cordycepin and adenosine in the products of Cordyceps spp. African Journal of Microbiology Research. 2009, 3(12): 957-961.

     [29] Zhou XW, Gong ZH, Su Y, Lin J, Tang KX. Cordyceps fungi: natural products, pharmacological functions and developmental products. Journal of Pharmacy and Pharmacology. 2009, 61(3):279-291.

     [30] Zhou XW, Li QZ, Yin YZ, Chen YY, Lin J. Identification of medicinal Ganoderma species based on PCR with specific primers and PCR-RFLP. Planta Medica. 2008, 74(2): 197-200.

     [31] Zhou XW, Wei YM, Zhu HF, Wang ZN, Lin J, Liu L, Tang KX. Protoplast formation, regeneration and transformation from the taxol-producing fungus Ozonium sp. African Journal of Biotechnology. 2008, 7 (12): 2017-2024.

     [32] Zhou XW, Lin J, Yin YZ, Zhao JY, Sun XF, Tang KX. Ganodermataceae: natural products and their related pharmacological functions. American Journal of Chinese Medicine. 2007, 35(4): 559-574.

     [33] Zhou XW, Lin J, Yin YZ, Sun XF, Tang KX. Participation in Research Program: a novel course in undergraduate education of life science. Biochemistry and Molecular Biology Education. 2007, 35(5):322-327

     [34] Zhou XW, Lin J, Yin YZ, Li QZ, Zhao JY, Tang KX. Comparison of rapid DNA extraction methods applied to PCR identification of medicinal mushroom Ganoderma spp. Preparative Biochemistry & Biotechnology. 2007, 37(4): 369- 380.

     [35] Zhou XW, Jiang H, Lin J, Tang KX. Cytotoxic activities of Coriolus versicolor (Yunzhi) extracts on human liver cancer and breast cancer cell line. African Journal of Biotechnology. 2007, 6(15):1740-1743.

     [36] Zhou XW, Wang ZN, Jiang KJ, Wei YM, Lin J, Sun XF, Tang KX. Screening of taxol-producing endophytic fungi from Taxus chinensis var. mairei. Applied Biochemistry and Microbiology. 2007, 43(4):439-443.

     [37] Zhou XW, Lin J, Zhang L, Chen ZH, Yin YZ, Guo BH, Sun XF and Tang KX. The development of biotechnology education in China. Biochemistry and Molecular Biology Education. 2006, 34(2): 141-147.

 

授权专利

  (1)周选围,孔应予,丛蔚然. 黑灵芝真菌免疫调节蛋白的制备方法及其应用。专利号:201410009107.2. (授权日:2016-08-30)

  (2)周选围,丛蔚然. 一种属内重组真菌免疫调节蛋白的制备方法及其应用. 专利号:201310167203.5. (授权日:2015-05-27)

  (3)汪新,周选围.  青稞胚芽米的制备方法. 专利号:ZL 201310441514.6. (授权日:2015-06-19)

  (4)周选围,王雪飞,李奇璋,苏恺奇,丛蔚然. 灵芝属间的重组真菌免疫调节蛋白基因、该基因编码的蛋白及其应用。专利号: ZL 2011 1 0068761.7 (授权日:2013-05-1)

  (5)周选围,王雪飞,李奇璋,苏恺奇,丛蔚然. 灵芝属内重组的真菌免疫调节蛋白基因、该基因编码的蛋白及其应用。专利号: ZL 2011 1 0068813.0 (授权日:2013-05-01)

  (6) 李奇璋,周选围. 真菌免疫调节蛋白基因启动子、重组载体及宿主细胞. 专利号:ZL 2009 1 0309882.9 (授权日:2012-07-04)

  (7) 周选围,龚振华,唐克轩. 北冬虫夏草甘油醛-3-磷酸脱氢酶基因启动子. 专利号:ZL 2009 1 0046694.1 (授权日:2012-06-13)

  (8)汪新, 周选围. 虫草多糖含片及其制备方法. 专利号ZL2008 1 0036761.7(授权日:2011-09-21)

  (9)周选围, 林娟, 李奇璋, 尹燡周, 唐克轩. 利用特异基因序列鉴别药用灵芝的检测方法.专利号: ZL2007 1 0170772.X. (授权日:2010-06-30)

Copyright 2016 manbetx体育3.0下载
地址:上海市闵行区东川路800号 电话:021 - 34205866 备案:沪交ICP备20101025

技术支持: 维程互联